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NBCRC : THE  Research  TEAM

5/15/2024

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We are going to start introducing some of the researchers from The Nottingham Breast Cancer Research Centre, so that you can find out a bit more about the wonderful work they do and why we are so passionate about the groundbreaking research, that our fundraising supports!
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Professor Stewart Martin (NBCRC Director)

Stop the spread
My team focuses on stopping breast cancer from spreading around the body (a process called metastasis) and on improving treatments. By working with patient samples we discovered proteins (called calpains) that help breast cancer cells travel through lymphatic vessels, and are now working on ways to halt this process. We aim to inhibit the calpain proteins and see how this affects the cancer cells’ ability to migrate elsewhere. 
Picture

​We’ve also found that calpains influence how breast cancer cells respond to conventional treatments, so by targeting them we can get a real ‘double whammy’ that has the potential to help thousands of women around the world.

We are also working with chemists and pharmacists, locally and from around the UK, who have developed new/novel drugs. We are testing these, growing breast cancer cells in the lab, in combination with radiotherapy to make the treatment more efficient whilst minimising any side-effects. Such drugs, and combinations, will offer hope to patients with cancers that are currently difficult to treat and that may be resistant to conventional therapies

If you have not yet, purchased your Boobie Ball tickets, we urge you to do so, as soon as possible as they are selling fast!
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